Make the rub mixture. In a small bowl, mix together the paprika, Italian seasoning, garlic powder, onion powder, salt, and pepper.
Prep the chicken. Start by preheating your air fryer to 380°F. Pat the chicken drumsticks dry with paper towels to ensure the seasoning sticks well. Brush each drumstick with olive oil on both sides. Generously coat the chicken all over with the spice rub.
Air fry the chicken. Arrange the chicken drumsticks in the air fryer basket, ensuring they are in a single layer. Air fry for 10 minutes, then flip them over and cook for another 10 minutes. If you prefer extra crispy skin and they aren't crispy enough, cook for an additional 5 minutes, keeping a close watch to avoid burning. The chicken is done when it reaches an internal temperature of 165°F.